apalutamide will minimize the level or result of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a robust CYP2C19 inducer, with medicine that happen to be CYP2C19 substrates may end up in decreased exposure to these medications.fentanyl iontophoretic transdermal proce